Abstract: Navigation safety of cruise ships is one of the hot issues as its risk level is higher than other types of mar-itime transportation.According to navigational conditions,factors for safety evaluation of cruise ships at Qingdao port are classified into three first-grade indices:human,ship,and environment.Each first-grade index is further divided into sec-ond-grade indices.A cloud model is used to evaluate navigation safety of cruise ships in order to perform uncertainty map-ping analysis between evaluation factors and comments.The entropy weight method is used to define the weights of indi-ces.One cruise ship at Qingdao port is selected as a case study to apply the approach based on the cloud model and the en-tropy weight method.The results show that the drops of the cloud model for the target cruise are mainly distributed in EX=83.73,followed the scope of"relatively safe".This approach reconciles both fuzziness and randomness.Its intuition and effectiveness presents a new insight to analyze safety problems of cruise ships.